| Mirko Gruden | |
| Birth Date: | 22 June 1911 |
| Birth Place: | Monfalcone, Italy |
| Death Place: | Grado, Friuli-Venezia Giulia, Italy |
| Position: | Midfielder |
| Years1: | 1928–1931 |
| Years2: | 1931–1932 |
| Years3: | 1932–1933 |
| Years4: | 1933–1935 |
| Years5: | 1935–1937 |
| Years6: | 1937–1938 |
| Years7: | 1938–1939 |
| Years8: | 1939–1940 |
| Years9: | 1940–1943 |
| Clubs7: | Pro Gorizia |
| Clubs9: | Monfalcone |
| Caps2: | 32 |
| Caps3: | 1 |
| Caps4: | 56 |
| Caps5: | 20 |
| Caps6: | 17 |
| Caps8: | 5 |
| Goals2: | 0 |
| Goals3: | 0 |
| Goals4: | 1 |
| Goals5: | 0 |
| Goals6: | 1 |
| Goals8: | 0 |
Mirko Gruden (June 22, 1911 Monfalcone - September 12, 1967 Grado) was an Italian professional football player.