Mir-589 microRNA precursor family explained

mir-589
Symbol:	mir-589
Rfam:	RF00987
Mirbase Family:	MIPF0000496
Rna Type:	microRNA
Tax Domain:	Eukaryota

In molecular biology mir-589 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

Molecular targets

miR-589 has been implicated in the regulation of antimicrobial targets in bovine lung alveolar macrophages, and alongside other miRNAs has been suggested to play a part in the immune response against Mycobacterium tuberculosis.^[1] It has additionally been linked to HLA-G expression, having been found to target the 3'UTR 14-base pair sequence region of the HLA-G gene.^[2]

See also

• MicroRNA

Notes and References

1. Xu G, Zhang Y, Jia H, Li J, Liu X, Engelhardt JG, etal . Cloning and identification of microRNAs in bovine alveolar macrophages. . Mol Cell Biochem . 2009 . 332 . 1–2 . 9–16 . 19507003 . 10.1007/s11010-009-0168-4 . 10508574 .
2. Castelli EC, Moreau P, Oya e Chiromatzo A, Mendes-Junior CT, Veiga-Castelli LC, Yaghi L, etal . In silico analysis of microRNAS targeting the HLA-G 3' untranslated region alleles and haplotypes. . Hum Immunol . 2009 . 70 . 12 . 1020–5 . 19664672 . 10.1016/j.humimm.2009.07.028 .