Mir-503 microRNA precursor family explained

mir-503
Symbol:	mir-503
Rfam:	RF00753
Mirbase Family:	MIPF0000183
Rna Type:	microRNA
Tax Domain:	Eukaryota

In molecular biology mir-503 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

See also

• MicroRNA

Further reading

• Cheng G, Sun S, Wang Z, Jin S . Investigation of the interaction between the MIR-503 and CD40 genes in irradiated U937 cells . Radiation Oncology . 7 . 38 . March 2012 . 22429276 . 3325872 . 10.1186/1748-717X-7-38 . free .
• Lu YC, Chen YJ, Wang HM, Tsai CY, Chen WH, Huang YC, Fan KH, Tsai CN, Huang SF, Kang CJ, Chang JT, Cheng AJ . Oncogenic function and early detection potential of miRNA-10b in oral cancer as identified by microRNA profiling . Cancer Prevention Research . 5 . 4 . 665–74 . April 2012 . 22318752 . 10.1158/1940-6207.CAPR-11-0358 . free .
• Zhu H, Li Y, Qu S, Luo H, Zhou Y, Wang Y, Zhao H, You Y, Xiao X, Zuo X . MicroRNA expression abnormalities in limited cutaneous scleroderma and diffuse cutaneous scleroderma . Journal of Clinical Immunology . 32 . 3 . 514–22 . June 2012 . 22307526 . 10.1007/s10875-011-9647-y . 15408954 .
• Cui YH, Xiao L, Rao JN, Zou T, Liu L, Chen Y, Turner DJ, Gorospe M, Wang JY . miR-503 represses CUG-binding protein 1 translation by recruiting CUGBP1 mRNA to processing bodies . Molecular Biology of the Cell . 23 . 1 . 151–62 . January 2012 . 22072795 . 3248894 . 10.1091/mbc.E11-05-0456 .
• Özata DM, Caramuta S, Velázquez-Fernández D, Akçakaya P, Xie H, Höög A, Zedenius J, Bäckdahl M, Larsson C, Lui WO . The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma . Endocrine-Related Cancer . 18 . 6 . 643–55 . October 2011 . 21859927 . 3201061 . 10.1530/ERC-11-0082 .
• Nie Y, Han BM, Liu XB, Yang JJ, Wang F, Cong XF, Chen X . Identification of MicroRNAs involved in hypoxia- and serum deprivation-induced apoptosis in mesenchymal stem cells . International Journal of Biological Sciences . 7 . 6 . 762–8 . 2011 . 21698002 . 3119848 . 10.7150/ijbs.7.762 .
• Zhou J, Wang W . Analysis of microRNA expression profiling identifies microRNA-503 regulates metastatic function in hepatocellular cancer cell . Journal of Surgical Oncology . 104 . 3 . 278–83 . September 2011 . 21495032 . 10.1002/jso.21941 . 23582191 .
• Caporali A, Meloni M, Völlenkle C, Bonci D, Sala-Newby GB, Addis R, Spinetti G, Losa S, Masson R, Baker AH, Agami R, le Sage C, Condorelli G, Madeddu P, Martelli F, Emanueli C . Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia . Circulation . 123 . 3 . 282–91 . January 2011 . 21220732 . 10.1161/CIRCULATIONAHA.110.952325 . free .
• Finnerty JR, Wang WX, Hébert SS, Wilfred BR, Mao G, Nelson PT . The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases . Journal of Molecular Biology . 402 . 3 . 491–509 . September 2010 . 20678503 . 2978331 . 10.1016/j.jmb.2010.07.051 .
• Boominathan L . The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex . PLOS ONE . 5 . 5 . e10615 . May 2010 . 20485546 . 2868896 . 10.1371/journal.pone.0010615 . Blagosklonny . 2010PLoSO...510615B . Mikhail V . free .
• Sarkar S, Dey BK, Dutta A . MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A . Molecular Biology of the Cell . 21 . 13 . 2138–49 . July 2010 . 20462953 . 2893979 . 10.1091/mbc.E10-01-0062 .
• Wagner-Ecker M, Schwager C, Wirkner U, Abdollahi A, Huber PE . MicroRNA expression after ionizing radiation in human endothelial cells . Radiation Oncology . 5 . 25 . March 2010 . 20346162 . 2859352 . 10.1186/1748-717X-5-25 . free .
• Belian E, Kurucz R, Treue D, Lage H . Effect of YB-1 on the regulation of micro RNA expression in drug-sensitive and drug-resistant gastric carcinoma cells . Anticancer Research . 30 . 2 . 629–33 . February 2010 . 20332481 .
• Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A . MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing . Molecular Human Reproduction . 16 . 7 . 463–71 . July 2010 . 20215419 . 2882868 . 10.1093/molehr/gaq017 .
• Patnaik SK, Kannisto E, Knudsen S, Yendamuri S . Evaluation of microRNA expression profiles that may predict recurrence of localized stage I non-small cell lung cancer after surgical resection . Cancer Research . 70 . 1 . 36–45 . January 2010 . 20028859 . 10.1158/0008-5472.CAN-09-3153 . free .
• Forrest AR, Kanamori-Katayama M, Tomaru Y, Lassmann T, Ninomiya N, Takahashi Y, de Hoon MJ, Kubosaki A, Kaiho A, Suzuki M, Yasuda J, Kawai J, Hayashizaki Y, Hume DA, Suzuki H . Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation . Leukemia . 24 . 2 . 460–6 . February 2010 . 19956200 . 10.1038/leu.2009.246 . 1007.2689 . 2333658 .
• Corbetta S, Vaira V, Guarnieri V, Scillitani A, Eller-Vainicher C, Ferrero S, Vicentini L, Chiodini I, Bisceglia M, Beck-Peccoz P, Bosari S, Spada A . Differential expression of microRNAs in human parathyroid carcinomas compared with normal parathyroid tissue . Endocrine-Related Cancer . 17 . 1 . 135–46 . March 2010 . 19926710 . 10.1677/ERC-09-0134 . free .
• Lei L, Jin S, Gonzalez G, Behringer RR, Woodruff TK . The regulatory role of Dicer in folliculogenesis in mice . Molecular and Cellular Endocrinology . 315 . 1–2 . 63–73 . February 2010 . 19799966 . 2814883 . 10.1016/j.mce.2009.09.021 .
• Tömböl Z, Szabó PM, Molnár V, Wiener Z, Tölgyesi G, Horányi J, Riesz P, Reismann P, Patócs A, Likó I, Gaillard RC, Falus A, Rácz K, Igaz P . Integrative molecular bioinformatics study of human adrenocortical tumors: microRNA, tissue-specific target prediction, and pathway analysis . Endocrine-Related Cancer . 16 . 3 . 895–906 . September 2009 . 19546168 . 10.1677/ERC-09-0096 . free .
• Jiang Q, Feng MG, Mo YY . Systematic validation of predicted microRNAs for cyclin D1 . BMC Cancer . 9 . 194 . June 2009 . 19538740 . 2728105 . 10.1186/1471-2407-9-194 . free .
• Wang XH, Qian RZ, Zhang W, Chen SF, Jin HM, Hu RM . MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats . Clinical and Experimental Pharmacology & Physiology . 36 . 2 . 181–8 . February 2009 . 18986336 . 10.1111/j.1440-1681.2008.05057.x . 205458045 .
• Zhao JJ, Yang J, Lin J, Yao N, Zhu Y, Zheng J, Xu J, Cheng JQ, Lin JY, Ma X . Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis . Child's Nervous System . 25 . 1 . 13–20 . January 2009 . 18818933 . 10.1007/s00381-008-0701-x . 30117644 .
• Joglekar MV, Parekh VS, Hardikar AA . New pancreas from old: microregulators of pancreas regeneration . Trends in Endocrinology and Metabolism . 18 . 10 . 393–400 . December 2007 . 18023200 . 10.1016/j.tem.2007.10.001 . 29473837 .