Mir-497 microRNA precursor family explained

mir-497
Symbol:	mir-497
Rfam:	RF00793
Mirbase Family:	MIPF0000231
Rna Type:	microRNA
Tax Domain:	Eukaryota

In molecular biology mir-497 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

See also

• MicroRNA

Further reading

• Guo ST, Jiang CC, Wang GP, Li YP, Wang CY, Guo XY, Yang RH, Feng Y, Wang FH, Tseng HY, Thorne RF, Jin L, Zhang XD . MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer . Oncogene . 32 . 15 . 1910–20 . April 2013 . 22710713 . 3630484 . 10.1038/onc.2012.214 .
• Yang C, Wang C, Chen X, Chen S, Zhang Y, Zhi F, Wang J, Li L, Zhou X, Li N, Pan H, Zhang J, Zen K, Zhang CY, Zhang C . Identification of seven serum microRNAs from a genome-wide serum microRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas . International Journal of Cancer . 132 . 1 . 116–27 . January 2013 . 22674182 . 10.1002/ijc.27657 . free .
• Lajer CB, Garnæs E, Friis-Hansen L, Norrild B, Therkildsen MH, Glud M, Rossing M, Lajer H, Svane D, Skotte L, Specht L, Buchwald C, Nielsen FC . The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer . British Journal of Cancer . 106 . 9 . 1526–34 . April 2012 . 22472886 . 3341860 . 10.1038/bjc.2012.109 .
• Luense LJ, Veiga-Lopez A, Padmanabhan V, Christenson LK . Developmental programming: gestational testosterone treatment alters fetal ovarian gene expression . Endocrinology . 152 . 12 . 4974–83 . December 2011 . 22009729 . 3384818 . 10.1210/en.2011-1182 .
• Yadav S, Pandey A, Shukla A, Talwelkar SS, Kumar A, Pant AB, Parmar D . miR-497 and miR-302b regulate ethanol-induced neuronal cell death through BCL2 protein and cyclin D2 . The Journal of Biological Chemistry . 286 . 43 . 37347–57 . October 2011 . 21878650 . 3199482 . 10.1074/jbc.M111.235531 . free .
• Özata DM, Caramuta S, Velázquez-Fernández D, Akçakaya P, Xie H, Höög A, Zedenius J, Bäckdahl M, Larsson C, Lui WO . The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma . Endocrine-Related Cancer . 18 . 6 . 643–55 . October 2011 . 21859927 . 3201061 . 10.1530/ERC-11-0082 .
• Xu X, Jia R, Zhou Y, Song X, Wang J, Qian G, Ge S, Fan X . Microarray-based analysis: identification of hypoxia-regulated microRNAs in retinoblastoma cells . International Journal of Oncology . 38 . 5 . 1385–93 . May 2011 . 21373755 . 10.3892/ijo.2011.961 . free .
• Balatti V, Maniero S, Ferracin M, Veronese A, Negrini M, Ferrocci G, Martini F, Tognon MG . MicroRNAs dysregulation in human malignant pleural mesothelioma . Journal of Thoracic Oncology . 6 . 5 . 844–51 . May 2011 . 21358347 . 10.1097/JTO.0b013e31820db125 . free .
• Li D, Zhao Y, Liu C, Chen X, Qi Y, Jiang Y, Zou C, Zhang X, Liu S, Wang X, Zhao D, Sun Q, Zeng Z, Dress A, Lin MC, Kung HF, Rui H, Liu LZ, Mao F, Jiang BH, Lai L . Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer . Clinical Cancer Research . 17 . 7 . 1722–30 . April 2011 . 21350001 . 10.1158/1078-0432.CCR-10-1800 . free .
• Zhu W, Zhu D, Lu S, Wang T, Wang J, Jiang B, Shu Y, Liu P . miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2 . Medical Oncology . 29 . 1 . 384–91 . March 2012 . 21258880 . 10.1007/s12032-010-9797-4 . 26205260 .
• Rink C, Khanna S . MicroRNA in ischemic stroke etiology and pathology . Physiological Genomics . 43 . 10 . 521–8 . May 2011 . 20841499 . 3110894 . 10.1152/physiolgenomics.00158.2010 .
• Finnerty JR, Wang WX, Hébert SS, Wilfred BR, Mao G, Nelson PT . The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases . Journal of Molecular Biology . 402 . 3 . 491–509 . September 2010 . 20678503 . 2978331 . 10.1016/j.jmb.2010.07.051 .
• Wald AI, Hoskins EE, Wells SI, Ferris RL, Khan SA . Alteration of microRNA profiles in squamous cell carcinoma of the head and neck cell lines by human papillomavirus . Head & Neck . 33 . 4 . 504–12 . April 2011 . 20652977 . 3080748 . 10.1002/hed.21475 .
• Lehmann U, Streichert T, Otto B, Albat C, Hasemeier B, Christgen H, Schipper E, Hille U, Kreipe HH, Länger F . Identification of differentially expressed microRNAs in human male breast cancer . BMC Cancer . 10 . 109 . March 2010 . 20331864 . 2850898 . 10.1186/1471-2407-10-109 . free .
• Lindberg RL, Hoffmann F, Mehling M, Kuhle J, Kappos L . Altered expression of miR-17-5p in CD4+ lymphocytes of relapsing-remitting multiple sclerosis patients . European Journal of Immunology . 40 . 3 . 888–98 . March 2010 . 20148420 . 10.1002/eji.200940032 . 205786377 .
• Yin KJ, Deng Z, Huang H, Hamblin M, Xie C, Zhang J, Chen YE . miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia . Neurobiology of Disease . 38 . 1 . 17–26 . April 2010 . 20053374 . 2837803 . 10.1016/j.nbd.2009.12.021 .
• Olsen L, Klausen M, Helboe L, Nielsen FC, Werge T . MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats . PLOS ONE . 4 . 10 . e7225 . October 2009 . 19806225 . 2752988 . 10.1371/journal.pone.0007225 . Preiss . Thomas . free .
• Guo J, Miao Y, Xiao B, Huan R, Jiang Z, Meng D, Wang Y . Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues . Journal of Gastroenterology and Hepatology . 24 . 4 . 652–7 . April 2009 . 19175831 . 10.1111/j.1440-1746.2008.05666.x . 32936687 . free .
• Yan LX, Huang XF, Shao Q, Huang MY, Deng L, Wu QL, Zeng YX, Shao JY . MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis . RNA . 14 . 11 . 2348–60 . November 2008 . 18812439 . 2578865 . 10.1261/rna.1034808 .
• Flavin RJ, Smyth PC, Laios A, O'Toole SA, Barrett C, Finn SP, Russell S, Ring M, Denning KM, Li J, Aherne ST, Sammarae DA, Aziz NA, Alhadi A, Sheppard BL, Lao K, Sheils OM, O'Leary JJ . Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma . Modern Pathology . 22 . 2 . 197–205 . February 2009 . 18677302 . 10.1038/modpathol.2008.135 . free .