Mir-361 microRNA precursor family explained
| mir-361 |
| Symbol: | mir-361 |
| Rfam: | RF00744 |
| Mirbase Family: | MIPF0000172 |
| Rna Type: | microRNA |
| Tax Domain: | Eukaryota
|
In molecular biology mir-361 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. For example, miR-361-5p might act as a suppressor in triple-negative breast cancer (TNBC) by targeting RQCD1 to inhibit the EGFR/PI3K/Akt signaling pathway.[1]
See also
Further reading
- Xie T, Liang J, Guo R, Liu N, Noble PW, Jiang D . Comprehensive microRNA analysis in bleomycin-induced pulmonary fibrosis identifies multiple sites of molecular regulation . Physiological Genomics . 43 . 9 . 479–87 . May 2011 . 21266501 . 3110895 . 10.1152/physiolgenomics.00222.2010 .
- Li ZY, Na HM, Peng G, Pu J, Liu P . Alteration of microRNA expression correlates to fatty acid-mediated insulin resistance in mouse myoblasts . Molecular BioSystems . 7 . 3 . 871–7 . March 2011 . 21183973 . 10.1039/c0mb00230e . .
Notes and References
- Han J, Yu J, Dai Y, Li J, Guo M, Song J, Zhou X. Overexpression of miR-361-5p in triple-negative breast cancer (TNBC) inhibits migration and invasion by targeting RQCD1 and inhibiting the EGFR/PI3K/Akt pathway. Bosn J of Basic Med Sci [Internet]. 2019Feb.12 [cited 2020Apr.6];19(1):52-9. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3399
