Mir-326 microRNA precursor family explained
| mir-326 |
| Symbol: | mir-326 |
| Rfam: | RF00719 |
| Mirbase Family: | MIPF0000143 |
| Rna Type: | microRNA |
| Tax Domain: | Eukaryota
|
In molecular biology mir-326 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.
See also
Further reading
- D'Angelo D, Palmieri D, Mussnich P, Roche M, Wierinckx A, Raverot G, Fedele M, Croce CM, Trouillas J, Fusco A . Altered microRNA expression profile in human pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1 . The Journal of Clinical Endocrinology and Metabolism . 97 . 7 . E1128-38 . July 2012 . 22564666 . 10.1210/jc.2011-3482 . free .
- Hamada N, Fujita Y, Kojima T, Kitamoto A, Akao Y, Nozawa Y, Ito M . MicroRNA expression profiling of NGF-treated PC12 cells revealed a critical role for miR-221 in neuronal differentiation . Neurochemistry International . 60 . 8 . 743–50 . June 2012 . 22465943 . 10.1016/j.neuint.2012.03.010 . 40247078 .
- Sebastiani G, Grieco FA, Spagnuolo I, Galleri L, Cataldo D, Dotta F . Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity . Diabetes/Metabolism Research and Reviews . 27 . 8 . 862–6 . November 2011 . 22069274 . 10.1002/dmrr.1262 . 29304855 .
- Schaefer JS, Montufar-Solis D, Vigneswaran N, Klein JR . Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/- mice precedes expression in the colon . Journal of Immunology . 187 . 11 . 5834–41 . December 2011 . 22043014 . 3221883 . 10.4049/jimmunol.1100922 .
- Waschbisch A, Atiya M, Linker RA, Potapov S, Schwab S, Derfuss T . Glatiramer acetate treatment normalizes deregulated microRNA expression in relapsing remitting multiple sclerosis . PLOS ONE . 6 . 9 . e24604 . 2011 . 21949733 . 3174971 . 10.1371/journal.pone.0024604 . Kleinschnitz . Christoph . 2011PLoSO...624604W . free .
- Ralfkiaer U, Hagedorn PH, Bangsgaard N, Løvendorf MB, Ahler CB, Svensson L, Kopp KL, Vennegaard MT, Lauenborg B, Zibert JR, Krejsgaard T, Bonefeld CM, Søkilde R, Gjerdrum LM, Labuda T, Mathiesen AM, Grønbæk K, Wasik MA, Sokolowska-Wojdylo M, Queille-Roussel C, Gniadecki R, Ralfkiaer E, Geisler C, Litman T, Woetmann A, Glue C, Røpke MA, Skov L, Odum N . Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL) . Blood . 118 . 22 . 5891–900 . November 2011 . 21865341 . 3342856 . 10.1182/blood-2011-06-358382 .
- Junker A . Pathophysiology of translational regulation by microRNAs in multiple sclerosis . FEBS Letters . 585 . 23 . 3738–46 . December 2011 . 21453702 . 10.1016/j.febslet.2011.03.052 . free .
- Kefas B, Comeau L, Erdle N, Montgomery E, Amos S, Purow B . Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells . Neuro-Oncology . 12 . 11 . 1102–12 . November 2010 . 20667897 . 3098027 . 10.1093/neuonc/noq080 .
- Kefas B, Comeau L, Floyd DH, Seleverstov O, Godlewski J, Schmittgen T, Jiang J, diPierro CG, Li Y, Chiocca EA, Lee J, Fine H, Abounader R, Lawler S, Purow B . The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors . The Journal of Neuroscience . 29 . 48 . 15161–8 . December 2009 . 19955368 . 2823067 . 10.1523/JNEUROSCI.4966-09.2009 .
- Liang Z, Wu H, Xia J, Li Y, Zhang Y, Huang K, Wagar N, Yoon Y, Cho HT, Scala S, Shim H . Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1 . Biochemical Pharmacology . 79 . 6 . 817–24 . March 2010 . 19883630 . 2880168 . 10.1016/j.bcp.2009.10.017 .
- Du C, Liu C, Kang J, Zhao G, Ye Z, Huang S, Li Z, Wu Z, Pei G . MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis . Nature Immunology . 10 . 12 . 1252–9 . December 2009 . 19838199 . 10.1038/ni.1798 . 15500858 .
- Xu CF, Yu CH, Li YM . Regulation of hepatic microRNA expression in response to ischemic preconditioning following ischemia/reperfusion injury in mice . OMICS . 13 . 6 . 513–20 . December 2009 . 19780683 . 10.1089/omi.2009.0035 .
- Tang YF, Zhang Y, Li XY, Li C, Tian W, Liu L . Expression of miR-31, miR-125b-5p, and miR-326 in the adipogenic differentiation process of adipose-derived stem cells . OMICS . 13 . 4 . 331–6 . August 2009 . 19422302 . 10.1089/omi.2009.0017 .
- Ferretti E, De Smaele E, Miele E, Laneve P, Po A, Pelloni M, Paganelli A, Di Marcotullio L, Caffarelli E, Screpanti I, Bozzoni I, Gulino A . Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells . The EMBO Journal . 27 . 19 . 2616–27 . October 2008 . 18756266 . 2567402 . 10.1038/emboj.2008.172 .
