Mir-320 Explained

mir-320
Symbol:	mir-320
Rfam:	RF00736
Mirbase Family:	MIPF0000163
Rna Type:	microRNA
Tax Domain:	Eukaryota

In molecular biology mir-320 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

The biogenesis of miR-320 is different from the canonical Microprocessor-dependent miRNAs. The pre-miR-320 is transcribed directly as a precursor microRNA hairpin and thus contains a 5′ m7G-cap.

See also

• MicroRNA

References

^{[1] [2] [3] [4] [5] [6] [7] [8]}

Notes and References

1. Xia HF, Jin XH, Song PP, Cui Y, Liu CM, Ma X . Temporal and spatial regulation of miR-320 in the uterus during embryo implantation in the rat. . Int J Mol Sci . 11 . 2 . 719–730 . 2010 . 20386663 . 10.3390/ijms11020719 . 2852863. free .
2. Duan H, Jiang Y, Zhang H, Wu Y . MiR-320 and miR-494 affect cell cycles of primary murine bronchial epithelial cells exposed to benzo[a]pyrene . Toxicol in Vitro . 24 . 3 . 928–935 . 2010 . 19925859 . 10.1016/j.tiv.2009.11.013.
3. Ling HY, Ou HS, Feng SD, Zhang XY, Tuo QH, Chen LX, Zhu BY, Gao ZP, Tang CK, Yin WD, Zhang L, Liao DF . Changes in microRNA profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes . Clin Exp Pharmacol Physiol . 36. 9. e32–e39. 2009 . 19473196 . 10.1111/j.1440-1681.2009.05207.x. 10568446 .
4. Ren XP, Wu J, Wang X, Sartor MA, Qian J, Jones K, Nicolaou P, Pritchard TJ, Fan GC . MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20 . Circulation . 119 . 17 . 2357–2366 . 2009 . 19380620 . 10.1161/CIRCULATIONAHA.108.814145 . 2746735.
5. Schaar DG, Medina DJ, Moore DF, Strair RK, Ting Y . miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation . Exp Hematol . 37 . 2 . 245–255 . 2009 . 19135902 . 10.1016/j.exphem.2008.10.002. free .
6. Wang XH, Qian RZ, Zhang W, Chen SF, Jin HM, Hu RM . MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats . Clin Exp Pharmacol Physiol . 36 . 2 . 181–188 . 2009 . 18986336 . 10.1111/j.1440-1681.2008.05057.x. 205458045 .
7. Ling. HY . Ou, HS . Feng, SD . Zhang, XY . Tuo, QH . Chen, LX . Zhu, BY . Gao, ZP . Tang, CK . Yin, WD . Zhang, L . Liao, DF. CHANGES IN microRNA (miR) profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes.. Clinical and Experimental Pharmacology & Physiology. September 2009. 36. 9. e32–9. 19473196. 10.1111/j.1440-1681.2009.05207.x. 10568446 .
8. Xie. M . Li, M . Vilborg, A . Lee, N . Yartseva, V . Sestan, N . Steitz, J . Mammalian 5′-Capped MicroRNA Precursors that Generate a Single MicroRNA.. Cell. September 2013. 155. 7. 1568–1580. 24360278 . 10.1016/j.cell.2013.11.027 . 3899828.