Mir-23 microRNA precursor family explained

mir-23
Symbol:	mir-23
Rfam:	RF00642
Mirbase Family:	22
Rna Type:	microRNA
Tax Domain:	Eukaryota

In molecular biology mir-23 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.^[1]

See also

• MicroRNA

Further reading

• Rathore MG, Saumet A, Rossi JF, de Bettignies C, Tempé D, Lecellier CH, Villalba M . The NF-κB member p65 controls glutamine metabolism through miR-23a . The International Journal of Biochemistry & Cell Biology . 44 . 9 . 1448–56 . September 2012 . 22634383 . 10.1016/j.biocel.2012.05.011 .
• Brunner S, Herndler-Brandstetter D, Arnold CR, Wiegers GJ, Villunger A, Hackl M, Grillari J, Moreno-Villanueva M, Bürkle A, Grubeck-Loebenstein B . Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death . Aging Cell . 11 . 4 . 579–87 . August 2012 . 22435726 . 3427896 . 10.1111/j.1474-9726.2012.00819.x .
• Li JS, Yao ZX . MicroRNAs: novel regulators of oligodendrocyte differentiation and potential therapeutic targets in demyelination-related diseases . Molecular Neurobiology . 45 . 1 . 200–12 . February 2012 . 22218763 . 10.1007/s12035-011-8231-z . 16920536 .
• Bang C, Fiedler J, Thum T . Cardiovascular importance of the microRNA-23/27/24 family . Microcirculation . 19 . 3 . 208–14 . April 2012 . 22136461 . 10.1111/j.1549-8719.2011.00153.x . 36926552 .
• Garcia DM, Baek D, Shin C, Bell GW, Grimson A, Bartel DP . Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs . Nature Structural & Molecular Biology . 18 . 10 . 1139–46 . September 2011 . 21909094 . 3190056 . 10.1038/nsmb.2115 .
• Lagendijk AK, Goumans MJ, Burkhard SB, Bakkers J . MicroRNA-23 restricts cardiac valve formation by inhibiting Has2 and extracellular hyaluronic acid production . Circulation Research . 109 . 6 . 649–57 . September 2011 . 21778427 . 10.1161/CIRCRESAHA.111.247635 . free . 20.500.11755/a71e06f3-504b-430c-8f38-fcc2de682b44 . free .
• Lin H, Qian J, Castillo AC, Long B, Keyes KT, Chen G, Ye Y . Effect of miR-23 on oxidant-induced injury in human retinal pigment epithelial cells . Investigative Ophthalmology & Visual Science . 52 . 9 . 6308–14 . August 2011 . 21693609 . 10.1167/iovs.10-6632 . free .
• Schotte D, Akbari Moqadam F, Lange-Turenhout EA, Chen C, van Ijcken WF, Pieters R, den Boer ML . Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia . Leukemia . 25 . 9 . 1389–99 . September 2011 . 21606961 . 10.1038/leu.2011.105 . free .
• Zhou Q, Gallagher R, Ufret-Vincenty R, Li X, Olson EN, Wang S . Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23~27~24 clusters . Proceedings of the National Academy of Sciences of the United States of America . 108 . 20 . 8287–92 . May 2011 . 21536891 . 3100947 . 10.1073/pnas.1105254108 . free .
• Song YJ, Tian XB, Zhang S, Zhang YX, Li X, Li D, Cheng Y, Zhang JN, Kang CS, Zhao W . Temporal lobe epilepsy induces differential expression of hippocampal miRNAs including let-7e and miR-23a/b . Brain Research . 1387 . 134–40 . April 2011 . 21376023 . 10.1016/j.brainres.2011.02.073 . 22862355 .
• Farrell BC, Power EM, Mc Dermott KW . Developmentally regulated expression of Sox9 and microRNAs 124, 128 and 23 in neuroepithelial stem cells in the developing spinal cord . International Journal of Developmental Neuroscience . 29 . 1 . 31–6 . February 2011 . 20937378 . 10.1016/j.ijdevneu.2010.10.001 . 5197368 .
• Calissano M, Latchman DS . Cell-specific regulation of the pro-survival Brn-3b transcription factor by microRNAs . Molecular and Cellular Neurosciences . 45 . 4 . 317–23 . December 2010 . 20609388 . 10.1016/j.mcn.2010.06.015 . 26638943 .
• Safdar A, Abadi A, Akhtar M, Hettinga BP, Tarnopolsky MA . miRNA in the regulation of skeletal muscle adaptation to acute endurance exercise in C57Bl/6J male mice . PLOS ONE . 4 . 5 . e5610 . 2009 . 19440340 . 2680038 . 10.1371/journal.pone.0005610 . 2009PLoSO...4.5610S . Lucia . Alejandro . free .
• Lin ST, Fu YH . miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination . Disease Models & Mechanisms . 2 . 3–4 . 178–88 . 2009 . 19259393 . 2650193 . 10.1242/dmm.001065 .
• Kulshreshtha R, Ferracin M, Wojcik SE, Garzon R, Alder H, Agosto-Perez FJ, Davuluri R, Liu CG, Croce CM, Negrini M, Calin GA, Ivan M . A microRNA signature of hypoxia . Molecular and Cellular Biology . 27 . 5 . 1859–67 . March 2007 . 17194750 . 1820461 . 10.1128/MCB.01395-06 .
• Kutay H, Bai S, Datta J, Motiwala T, Pogribny I, Frankel W, Jacob ST, Ghoshal K . Downregulation of miR-122 in the rodent and human hepatocellular carcinomas . Journal of Cellular Biochemistry . 99 . 3 . 671–8 . October 2006 . 16924677 . 3033198 . 10.1002/jcb.20982 .
• Smirnova L, Gräfe A, Seiler A, Schumacher S, Nitsch R, Wulczyn FG . Regulation of miRNA expression during neural cell specification . The European Journal of Neuroscience . 21 . 6 . 1469–77 . March 2005 . 15845075 . 10.1111/j.1460-9568.2005.03978.x . 23941766 .
• Cheng AM, Byrom MW, Shelton J, Ford LP . Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis . Nucleic Acids Research . 33 . 4 . 1290–7 . 2005 . 15741182 . 552951 . 10.1093/nar/gki200 .
• Kawasaki H, Taira K . Functional analysis of microRNAs during the retinoic acid-induced neuronal differentiation of human NT2 cells . Nucleic Acids Research. Supplement . 3 . 3 . 243–4 . 2003 . 14510471 . 10.1093/nass/3.1.243 . free .

Notes and References

1. Qureshi A, Thakur N, Monga I, Thakur A, Kumar M . VIRmiRNA: a comprehensive resource for experimentally validated viral miRNAs and their targets . Database . 2014 . bau103 . 1 January 2014 . 25380780 . 4224276 . 10.1093/database/bau103.