Mir-166 microRNA precursor explained

mir-166 microRNA precursor
Symbol:mir-166
Rfam:RF00075
Mirbase:MI0000201
Mirbase Family:MIPF0000004
Rna Type:Gene
miRNA
Tax Domain:Eukaryota

The plant mir-166 microRNA precursor is a small non-coding RNA gene. This microRNA (miRNA) has now been predicted or experimentally confirmed in a wide range of plant species.[1] microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product.[2] In this case the mature sequence comes from the 3' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences.[3] The mature products are thought to have regulatory roles through complementarity to messenger RNA.

External links

Notes and References

  1. Web site: miRNA gene family: MIR166. mirBASE. University of Manchester. 5 September 2011.
  2. Ambros V . microRNAs: tiny regulators with great potential . Cell . 107 . 7 . 823–6 . December 2001 . 11779458 . 10.1016/S0092-8674(01)00616-X . free .
  3. Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP . MicroRNAs in plants . Genes & Development . 16 . 13 . 1616–26 . July 2002 . 12101121 . 186362 . 10.1101/gad.1004402 .