Mir-156 microRNA precursor explained
| miR156 microRNA precursor |
| Symbol: | miR156 |
| Rfam: | RF00073 |
| Mirbase: | MI0000178 |
| Mirbase Family: | MIPF0000008 |
| Rna Type: | Gene
- miRNA
|
| Tax Domain: | Eukaryota |
MicroRNA (miRNA) precursor miR156 is a family of plant non-coding RNA. This microRNA has now been predicted or experimentally confirmed in a range of plant species (MIPF0000008). miR156 functions in the induction of flowering by suppressing the transcripts of SQUAMOSA-PROMOTER BINDING LIKE (SPL) transcription factors gene family. It was suggested that the loading into ARGONAUTE1 and ARGONAUTE5 is required for miR156 functionality in Arabidopsis thaliana.[1] In plants the precursor sequences may be longer, and the carpel factory (caf) enzyme appears to be involved in processing. In this case the mature sequence comes from the 5' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences. The extents of the hairpin precursors are not generally known and are estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity to mRNA.
This miRNA is involved in control of reproductive structures in liverworts.[2]
Further reading
- Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP . MicroRNAs in plants . Genes & Development . 16 . 13 . 1616–26 . July 2002 . 12101121 . 186362 . 10.1101/gad.1004402 .
- Ambros V . microRNAs: tiny regulators with great potential . Cell . 107 . 7 . 823–6 . December 2001 . 11779458 . 10.1016/S0092-8674(01)00616-X . 14574186 . free .
- Zhang B, Pan X . Expression of microRNAs in cotton . Molecular Biotechnology . 42 . 3 . 269–74 . July 2009 . 19288227 . 10.1007/s12033-009-9163-y . 207376300 .
- Yu S, Galvão VC, Zhang YC, Horrer D, Zhang TQ, Hao YH, Feng YQ, Wang S, Schmid M, Wang JW . Gibberellin regulates the Arabidopsis floral transition through miR156-targeted SQUAMOSA promoter binding-like transcription factors . The Plant Cell . 24 . 8 . 3320–32 . August 2012 . 22942378 . 3462634 . 10.1105/tpc.112.101014 .
External links
Notes and References
- Roussin-Léveillée. Charles. Silva-Martins. Guilherme. Moffett. Peter. ARGONAUTE5 Represses Age-Dependent Induction of Flowering through Physical and Functional Interaction with miR156 in Arabidopsis. Plant Cell Physiology. 2020. 61. 5. 957–966. 10.1093/pcp/pcaa022. 32105323.
- Tsuzuki. Masayuki. Futagami. Kazutaka. Shimamura. Masaki. Inoue. Chikako. Kunimoto. Kan. Oogami. Takashi. Tomita. Yuki. Inoue. Keisuke. Kohchi. Takayuki. Yamaoka. Shohei. Araki. Takashi. Hamada. Takahiro. Watanabe. Yuichiro. An Early Arising Role of the MicroRNA156/529-SPL Module in Reproductive Development Revealed by the Liverwort Marchantia polymorpha. Current Biology. 2019. 29. 19. 3307–3314.e5. 0960-9822. 10.1016/j.cub.2019.07.084. 31543452. free.
