Minus-end-directed kinesin ATPase explained

Minus-end-directed kinesin ATPase
Ec Number:	3.6.4.5

Minus-end-directed kinesin ATPase is an enzyme with systematic name kinesin ATP phosphohydrolase (minus-end-directed).^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

ATP + H₂O

\rightleftharpoons ADP + phosphate

This enzyme catalyses movement towards the minus end of microtubules.

See also

• Kinesin

Notes and References

1. Henningsen U, Schliwa M . Reversal in the direction of movement of a molecular motor . Nature . 389 . 6646 . 93–6 . September 1997 . 9288974 . 10.1038/38022 .
2. Sharp DJ, Kuriyama R, Essner R, Baas PW . Expression of a minus-end-directed motor protein induces Sf9 cells to form axon-like processes with uniform microtubule polarity orientation . Journal of Cell Science . 110 (Pt 19) . 2373–80 . October 1997 . 9410876 .
3. Sablin EP, Case RB, Dai SC, Hart CL, Ruby A, Vale RD, Fletterick RJ . Direction determination in the minus-end-directed kinesin motor ncd . Nature . 395 . 6704 . 813–6 . October 1998 . 9796817 . 10.1038/27463 .