| Agency Name: | Ministry of Industry, Science, Technology and Innovation |
| Nativename: | Central Khmer: ក្រសួងឧស្សាហកម្ម វិទ្យាសាស្ត្រ បច្ចេកវិទ្យា និងនវានុវត្តន៍ |
| Jurisdiction: | Government of Cambodia |
| Headquarters: | 45 Preah Norodom Blvd, Phnom Penh 120203 |
| Minister1 Name: | Hem Vanndy |
| Minister1 Pfo: | Minister of Industry, Science, Technology and Innovation |
The Ministry of Industry, Science, Technology and Innovation (km|ក្រសួងឧស្សាហកម្ម វិទ្យាសាស្ត្រ បច្ចេកវិទ្យា និងនវានុវត្តន៍, UNGEGN:) is a government ministry responsible for industrial, science, technology, innovation policies in Cambodia. Its name was changed from the Ministry of Industry and Handicrafts in March 2020, in response to the fourth Industrial Revolution.[1] [2] The current minister is HEM Vanndy.