| Agency Name: | Ministry of Education and Science |
| Native Name: | Министерство за образование и наука (Macedonian) Ministria e Arsimit dhe Shkencës (Albanian) |
| Picture Caption: | The building which houses the Ministry |
| Formed: | 1991 (As a Ministry of modern Republic of Macedonia) |
| Jurisdiction: | Government of North Macedonia |
| Headquarters: | Skopje, |
| Minister1 Name: | Vesna Janevska, Minister of Education and Science |
| Child1 Agency: | Pedagogical Services Office |
| Child2 Agency: | Bureau for Development of the Education |
| Child3 Agency: | National Educational Inspectorate |
| Child4 Agency: | Authority for development and upgrading the education in the ethnicities' tongues |
The Ministry of Education and Science is a ministry of the Government of the Republic of North Macedonia, by virtue of section 23 of the Law of Organization and Acting of the Organs of State's Administration (Law Gazette of Republic of Macedonia no. 59/2000 from 21. July 2000). The Ministry does the work concerning:
As sectors of the Ministry, exist the following institutions:
| № | Portrait | Name (born-died) | Mandate commenced on | Mandate finished on | Length (in days) | Party/Coalition | Government | |
|---|---|---|---|---|---|---|---|---|
| of education (1991–2000) | ||||||||
| 1 | Dimitar Dimitrov (b. 1937) | 20 March 1991 | 5 September 1992 | Independent | First Government of Macedonia in 1991 | |||
| 2 | Dimitar Bajaldžiev (b. 1932) | 5 September 1992 | 20 December 1994 | SDSM | Second Government of Macedonia in 1992 | |||
| 3 | Emilija Simoska | 20 December 1994 | 23 February 1996 | SDSM | Third Government of Macedonia in 1994 | |||
| 4 | Sofija Todorova (b. 1947) | 23 February 1996 | 30 November 1998 | Independent | Third Government of Macedonia in 1994 | |||
| 5 | Nenad Novkovski (b. 1958) | 30 November 1998 | 28 December 1999 | VMRO-DPMNE | Fourth Government of Macedonia in 1998 | |||
| 6 | Gale Galev (b. 1943) | 28 December 1999 | 31 July 2000 | Independent | Fourth Government of Macedonia in 1998 | |||
| of science (1991–2000) | ||||||||
| 1 | Georgi Efremov (b. 1932) | 20 March 1991 | 5 September 1992 | Independent | First Government of Macedonia in 1991 | |||
| 2 | Aslan Selmani (1945–2011) | 5 September 1992 | 20 December 1994 | Independent | Second Government of Macedonia in 1992 | |||
| 3 | Sofija Todorova (b. 1947) | 20 December 1994 | 23 February 1996 | Independent | Third Government of Macedonia in 1994 | |||
| (2) | Aslan Selmani (1945–2011)(2nd mandate) | 23 February 1996 | 30 November 1998 | Independent | Third Government of Macedonia in 1994 | |||
| 4 | Merie Rushani (b. 1958) | 30 November 1998 | 28 December 1999 | PDSH | Fourth Government of Macedonia in 1998 | |||
| 5 | Nenad Novkovski (b. 1958) | 28 December 1999 | 31 July 2000 | Independent | Fourth Government of Macedonia in 1998 | |||
| of Education and Science (2000–present) | ||||||||
| 1 | Gale Galev (b. 1943) | 31 July 2000 | 1 November 2000 | Independent | Fourth Government of Macedonia in 1998 | |||
| 2 | Nenad Novkovski (b. 1958) | 1 November 2000 | 1 November 2001 | Independent | Fourth Government of Macedonia in 1998 | |||
| 3 | Azis Polozhani (b. 1957) | 1 November 2001 | 27 August 2006 | BDI | Fifth Government of Macedonia in 2002 | |||
| 4 | Sulejman Rushiti (b. 1972) | 27 August 2006 | 27 July 2008 | PDSH | Sixth Government of Republic of Macedonia in 2006 | |||
| 5 | Pero Stojanovski (b. 1970) | 27 July 2008 | 10 July 2009 | VMRO-DPMNE | Seventh Government of Macedonia in 2008 | |||
| 6 | Nikola Todorov (b. 1979) | 10 July 2009 | 5 June 2011 | VMRO-DPMNE | Seventh Government of Macedonia in 2008 | |||
| 7 | Panche Kralev (b. 1981) | 28 July 2011 | 28 May 2013 | VMRO-DPMNE | Eight Government of Macedonia in 2011 | |||
| 8 | Spiro Ristovski | 29 May 2013 | 19 June 2014 | VMRO-DPMNE | Ninth Government of Macedonia in 2013 | |||
| 9 | Abdylaqim Ademi | 20 June 2014 | 5 April 2016 | DUI | Tenth Government of Macedonia in 2014 | |||
| 10 | Pishtar Lutfiu | 5 April 2016 | 1 June 2017 | DUI | Eleventh Government of Macedonia in 2016 | |||
| 11 | Renata Deskoska | 1 June 2017 | 1 June 2018 | SDSM | Twelfth Government of Macedonia in 2017 | |||
| 12 | Arbër Ademi | 1 June 2018 | 30 August 2020 | DUI | Thirteenth Government of Macedonia in 2018 | |||
| 13 | Mila Carovska | 30 August 2020 | 17 January 2022 | SDSM | Fourteenth Government of Macedonia in 2020 | |||
| 14 | Jeton Shaqiri | 17 January 2022 | 23 June 2024 | DUI | Fourteenth Government of Macedonia in 2022 | |||