| Agency Name: | Ministry of Defence, Justice and Security |
| Type: | Ministry |
| Seal: | Coat of arms of Botswana.svg |
| Jurisdiction: | Government of Botswana |
| Minister1 Pfo: | Kagiso Mmusi |
The Ministry of Defence, Justice and Security of Botswana aims to provide safety, protection and promote human rights and rule of law via the implementation of pertinent policies and programming in order to achieve peace and tranquility. The ministry oversees the following departments:[1] [2]
| N | Picture | Name | Took office | Left office | |
|---|---|---|---|---|---|
| 1 | Seretse Khama | 1966 | 1966 | ||
| 2 | Quett Masire | 1966 | 1967 | ||
| 3 | Seretse Khama | 1967 | 1968 | ||
| 4 | Quett Masire | 1968 | 1970 | ||
| 5 | Seretse Khama | 1970 | 1975 | ||
| 6 | Quett Masire | 1975 | 1979 | ||
| 7 | Seretse Khama | 1979 | 1980 | ||
| 8 | Quett Masire | 1980 | 1982 | ||
| 9 | Ruth Williams Khama | 1982 | 1982 | ||
| 10 | Lenyeletse Seretse | 1982 | 1983 | ||
| 11 | Peter Mmusi | 1983 | 1989 | ||
| 12 | Gladys Olebile Masire | 1989 | 1992 | ||
| 13 | Festus Mogae | 1992 | 1 April 1998 | ||
| 14 | Barbara Mogae | 1998 | 1998 | ||
| 15 | Ian Khama | 1998 | 2008 | ||
| 16 | Tshekedi Khama II | 2008 | 2008 | ||
| 17 | Dikgakgamatso Ndelu Seretse | 2008 | 2010 | ||
| 18 | Lesego Motsumi | 2010 | 2011 | ||
| 19 | Mompati Merafhe | 2011 | 2012 | ||
| 20 | Lesego Motsumi | 2012 | 2012 | ||
| 21 | Dikgakgamatso Ndelu Seretse | 2012 | 2013 | ||
| 21 | Shaw Kgathi | 2013 | 2013 | ||
| 22 | Ponatshego Kedikilwe | 2013 | 2014 | ||
| 23 | Shaw Kgathi | 2014 | 2014 | ||
| 24 | Mokgweetsi Masisi | 2014 | 2015 | ||
| 25 | Neo Masisi | 2015 | 2015 | ||
| 26 | Shaw Kgathi | 2015 | 2018 | ||
| 27 | Mokgweetsi Masisi | 2018 | 2018 | ||
| 28 | Neo Masisi | 2018 | 2018 | ||
| 29 | Slumber Tsogwane | 2018 | 2018 | ||
| 30 | Dikgakgamatso Ndelu Seretse | 2018 | 2018 | ||
| 31 | Shaw Kgathi | 2018 | 2022 | ||
| 32 | Kagiso Mmusi | 2022 | Incumbent |