| Agency Name: | Ministry of National Defence |
| Nativename: | وزارة الدفاع الوطني |
| Headquarters: | Tunis, Tunisia |
| Formed: | 1957 |
| Jurisdiction: | Government of Tunisia |
| Chief1 Name: | Imed Memmich |
| Chief1 Position: | Minister of National Defence |
The Ministry of National Defence (ar|وزارة الدفاع الوطني) is a government ministry office of the Republic of Tunisia, responsible for coordinating and supervising all agencies and functions of the government concerned directly with national security and the Tunisian Armed Forces. Since 2021, the Minister of National Defence has been Imed Memmich.
This is a list of defence ministers of Tunisia.