| Ministry of Science, Technology and Innovation | |
| Native Name: | Portuguese: Ministério da Ciência, Tecnologia e Inovação |
| Agency Type: | Ministry |
| Seal: | Coat of arms of Brazil.svg |
| Seal Size: | 100px |
| Jurisdiction: | Federal government of Brazil |
| Headquarters: | Esplanada dos Ministérios, Bloco E Brasília, Federal District |
| Budget: | $13.32 b BRL (2023)[1] |
| Chief1 Name: | Luciana Santos (politician) |
| Chief1 Position: | Minister |
| Chief2 Name: | Luis Rebelo Fernandes |
| Chief2 Position: | Executive-Secretary |
| Chief3 Name: | Marcia Cristina Barbosa |
| Chief3 Position: | Secretary of Policies and Strategic Programs |
| Chief4 Name: | Inácio Arruda |
| Chief4 Position: | Secretary of Science and Technology for Social Development |
| Chief5 Name: | Guila Calheiros |
| Chief5 Position: | Secretary of Technological Development and Innovation |
| Chief6 Name: | Henrique de Oliveira Miguel |
| Chief6 Position: | Secretary of Science and Technology for Digital Transformation |
The Ministry of Science, Technology and Innovation (MCTI; Portuguese: Ministério da Ciência, Tecnologia e Inovação) of Brazil is the civilian cabinet organization which coordinates science, technology, and innovation activities in the country. It is headed by the Minister of Science, Technology and Innovation.