| Official Name: | Milofanovo |
| Native Name: | Милофаново |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Nikolsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 59.9°N 99°W[1] |
Milofanovo (Russian: Милофаново) is a rural locality (a village) in Zelentsovskoye Rural Settlement, Nikolsky District, Vologda Oblast, Russia. The population was 131 as of 2002.[2]
Milofanovo is located 59 km northwest of Nikolsk (the district's administrative centre) by road. Senino is the nearest rural locality.[3]