| Mill Run | |
| Name Other: | Tributary to Neshannock Creek |
| Map Size: | 300 |
| Pushpin Map: | USA Pennsylvania#USA |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Location of Mill Run mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States of America |
| Subdivision Type2: | State |
| Subdivision Name2: | Pennsylvania |
| Subdivision Type3: | County |
| Subdivision Name3: | Mercer |
| Subdivision Type4: | Township |
| Subdivision Name4: | Springfield |
| Length: | 4.69miles[1] |
| Discharge1 Location: | near Milburn, Pennsylvania |
| Discharge1 Avg: | 7.54cuft/s at mouth with Neshannock Creek[2] |
| Source1: | wetland at divide between Mill Run and Wolf Creek |
| Source1 Location: | about 0.5 miles southeast of Blacktown, Pennsylvania |
| Source1 Coordinates: | 41.1558°N -80.1603°W[3] |
| Source1 Elevation: | 1270feet[4] |
| Mouth: | Neshannock Creek |
| Mouth Location: | about 0.25 miles southeast of Milburn, Pennsylvania |
| Mouth Coordinates: | 41.1647°N -80.2244°W |
| Mouth Elevation: | 1048feet |
| Progression: | Neshannock Creek → Shenango River → Beaver River → Ohio River → Mississippi River → Gulf of Mexico |
| River System: | Beaver River |
| Tributaries Left: | unnamed tributaries |
| Tributaries Right: | unnamed tributaries |
Mill Run is a tributary to Neshannock Creek in western Pennsylvania. The stream rises in southeastern Mercer County and flows generally northwest entering Neshannock Creek near Milburn, Pennsylvania. Mill Run watershed is roughly 36% agricultural, 56% forested and the rest is other uses.[2]