Mill Rock Creek is a stream in Crawford and Iron counties in the U.S. state of Missouri. It is a tributary of Huzzah Creek.
The stream headwaters arise in the northwest corner of Iron County just north of Viburnum (at 37.7333°N -91.1278°W) and the stream flows northwest to its confluence with Huzzah Creek in Crawford County (at 37.7667°N -91.1714°W).[1] Possum Trot Creek enters the Huzzah just upstream from Mill Rock Creek.[1]
Mill Rock Creek was named for the fact the watercourse was the source of millstones.[2]