| Mikro Seirini | |
| Name Local: | Μικρό Σειρήνι |
| Periph: | West Macedonia |
| Periphunit: | Grevena |
| Municunit: | Grevena |
| Community: | Megalo Seirini |
| Population: | 74 |
| Population As Of: | 2021 |
| Coordinates: | 40.13°N 46.6°W |
| Postal Code: | 511 00 |
| Area Code: | +30-2462 |
| Licence: | PN |
| Elevation: | 640 |
Mikro Seirini is a village of the Grevena municipality. Before the 1997 local government reform it was a part of the community of Megalo Seirini.[1] The 2021 census recorded 74 residents in the village.