| Official Name: | Mikhaylovka 2-ya |
| Native Name: | Михайловка 2-я |
| Native Name Lang: | ru |
| Settlement Type: | Selo |
| Pushpin Map: | Russia Voronezh Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Type1: | Region |
| Subdivision Name1: | Voronezh Oblast |
| Subdivision Type2: | County |
| Subdivision Type3: | District |
| Subdivision Name3: | Paninsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 51.7333°N 98°W[1] |
Mikhaylovka 2-ya (Russian: links=no|Михайловка 2-я) is a selo in Dmitriyevskoye Rural Settlement, Paninsky District, Voronezh Oblast, Russia. The population is 162 as of 2010.[2] There are five streets.[3]
Mikhaylovka 2-ya is located on the Rtishchevo River, 26 km northwest of Panino (the district's administrative centre) by road. Nikolskoye 1-ye is the nearest rural locality.[4]