Mikael Pittet Explained

Mikaël Pittet
Field:Clinical Research, Immune System, Cancer Immunotherapy, Molecular Imaging
Work Institutions:University of Geneva, Geneva University Hospitals, Swiss Institute for Experimental Cancer Research, Ludwig Institute for Cancer Research.

Mikaël Pittet is a Swiss research scientist.

Biography

Mikaël J. Pittet (born May 23, 1975, in Lausanne (Switzerland) is Professor of Immunology at the University of Geneva (UNIGE),[1] holder of the ISREC Foundation Chair in immuno-oncology [2] and full Member of the Ludwig Institute for Cancer Research Lausanne Branch.[3]

Mikaël Pittet completed his PhD thesis in Immunology at the Ludwig Institute for Cancer Research and graduated from University of Lausanne (Switzerland) in 2001. Following his degrees, he moved to Boston (USA) where he pursued post-doctoral research at Massachusetts General Hospital (MGH), Harvard Medical School (HMS) and Dana–Farber Cancer Institute (DFCI). Pittet became Assistant Professor at HMS in 2006, Associate Professor in 2013, and Full Professor in 2019 (Department of radiology). He was named Samana Cay MGH Research Scholar in 2015 [4] and appointed Director of the Cancer immunology program at the Center for systems biology in 2016.[5] He was also a member of the Dana-Farber/Harvard Cancer Center and Immunology Program at Harvard Medical School.[6]

He joined the University of Geneva (Switzerland) in 2020 as a Full Professor of Immunology, and holds the ISREC Foundation Chair in immuno-oncology. He was appointed a full Member of the Ludwig Institute in 2021. Pittet also leads the Translational Research Center in Oncohaematology (CRTOH) at the University of Geneva since 2022 and is a member of the Center for inflammation research. He is equally a member of the Department of oncology of the Geneva University Hospitals.

The Pittet Lab is located in Lausanne (Switzerland) in the AGORA cancer research center, which brings together interdisciplinary research groups of the Swiss Cancer Center Léman (SCCL) Léman (SCCL) working to accelerate the transfer of cancer research into the clinic.

Mikaël Pittet serves on the editorial board of the journals Cell Stress [7] and Cancer Immunology Research.[8]

Research

Pittet is a widely cited researcher [9] in cancer immunology and cancer immunotherapy, especially in the fields of innate and adaptive immunity. His research focuses on uncovering how the immune system controls cancer and other diseases and how it can be harnessed for therapy.[10] [11] [12] He is known for utilizing molecular imaging to track immune cells and drugs directly in vivo.[13] [14] Pittet's work has identified how cancers are regulated by various immune cells, including cytotoxic T cells, regulatory T cells, macrophages, monocytes, neutrophils, and dendritic cells. These cells are considered as drug targets in cancer immunotherapy.

Publications

As of 2022, Pittet has authored 146 publications in peer-reviewed journals and contributed to several textbooks. His work has been cited >40,000 times and he has an h-index of >80.

Awards and honors

Pittet's work has been honored with the 2015 Samana Cay MGH Research Scholarship Award,[15] the 2016 Robert Wenner Award,[16] the 2016 Distinguished Investigator Award [17] from the Academy of Radiology Research, and the 2017 MGH Mentoring Award.[18] He also received a Honorary Master of Arts Degree from Harvard University in 2019 and is recognized as a Highly Cited Researcher based on his multiple papers that rank in the top 1% by citations across fields and during the last decade.[19] [20] [21] [22]

Selected publications

Notes and References

  1. Web site: Mickaël Pittet - Département de pathologie et d'immunologie - UNIGE . 25 September 2020 .
  2. Web site: Appointment of Prof. Mikaël Pittet at the Ludwig Institute for Cancer Research .
  3. Web site: Ludwig Cancer Research .
  4. Web site: MGH Research Scholars 2015-2020 .
  5. Web site: Mikael J. Pittet, PhD - Mass General Advances in Motion .
  6. Web site: Mikael J. Pittet, PhD - Mass General Advances in Motion .
  7. Editorial Board. Cell Stress.
  8. Web site: Editorial Board - Cancer Immunology Research. cancerimmunolres.aacrjournals.org.
  9. Web site: Pittet Mikael - Google Scholar Citations. scholar.google.com.
  10. Uncovering cancer: How enlisting T cells can boost the power of immunotherapy. Nature Medicine . 10.1038/nm0917-1006. 23. 2017. 1006–1008. Keener AB. 9. 28886004. 205382518.
  11. Macrophages Play a Double Role in Cancer . The Scientist.
  12. Cancer-promoting cells are bred in the bone . Nature . 10.1038/d41586-017-07831-3. 552. 2017. 7683 . 8. 32080542 . 4401222 .
  13. PD-1 blockade: It's what's for dinner. Science Immunology . 10.1126/sciimmunol.aan8155. 2. 2017. eaan8155. Griffin GK. 12. 28783659. 44105794.
  14. Macrophages Promote Resistance to Checkpoint Inhibitors . Cancer Discovery. 2017 . 7 . 8 . 788 . 10.1158/2159-8290.CD-NB2017-081 . 28615281 . free .
  15. Web site: Mass General Research Scholars - Massachusetts General Hospital, Boston, MA. www.massgeneral.org.
  16. Web site: Robert Wenner-Preis. Krebsliga.
  17. Web site: Description of Award – The Academy for Radiology & Biomedical Imaging Research. www.acadrad.org. 13 August 2015 .
  18. Web site: MGH Center for Systems Biology :: Laboratories :: Base :: News .
  19. Web site: Highly Cited Researchers 2019. hcr.clarivate.com. 2018-12-14. https://web.archive.org/web/20190220122703/https://hcr.clarivate.com/#freeText%3Dpittet%26categories%3Dcross-field. 2019-02-20. dead.
  20. Web site: Highly Cited Researchers .
  21. Web site: Highly Cited Researchers .
  22. Web site: Highly Cited Researchers . 2023-01-18 . Clarivate . en.

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