| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Miguel López de la Serna | |
| Bishop of Islas Canarias | |
| Church: | Catholic Church |
| Diocese: | Diocese of Islas Canarias |
| Term: | 1486–1490 |
| Predecessor: | Juan de Frías |
| Death Date: | 1490 |
| Death Place: | Canary Islands, Spain |
Miguel López de la Serna, O.F.M. (also Michele Lopez de la Sorra) (died 1490) was a Roman Catholic prelate who served as Bishop of Islas Canarias (1486–1490).
Miguel López de la Serna was ordained a priest in the Order of Friars Minor.[1] On 29 Mar 1486, he was appointed during the papacy of Pope Innocent VIII as Bishop of Islas Canarias. He served as Bishop of Islas Canarias until his death in 1490.