Microsatellite enrichment explained

Microsatellite enrichment is a method in molecular biology used for enriching the amount of microsatellite sequences in a DNA sample. This can be achieved by designing oligonucleotide probes that hybridize with the repeats in the microsatellites and then pull out the probe/microsatellite complexes from the solution.[1] This has been shown to be a cost-effective method to sample the genetic diversity in non-model organisms.[2]

Notes and References

  1. Kaukinen KH, Supernault KJ, Miller KM . 2004 . Enrichment of tetranucleotide microsatellite loci from invertebrate species . Journal of Shellfish Research . 23 . 2 . 621.
  2. Jennings. TN . Knaus, BJ . Mullins, TD . Haig, SM . Cronn, RC. Multiplexed microsatellite recovery using massively parallel sequencing.. Molecular Ecology Resources. 2011-06-16. 21676207. 10.1111/j.1755-0998.2011.03033.x. 11. 6. 1060–7. 42109222 .

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