Michels syndrome explained

Synonyms:	Oculopalatoskeletal syndrome
Field:	Medical genetics

Michels syndrome is a syndrome characterised by intellectual disability, craniosynostosis, blepharophimosis, ptosis, epicanthus inversus,^{[1] [2]} highly arched eyebrows, and hypertelorism.^{[2] [3]} People with Michels syndrome vary in other symptoms such as asymmetry of the skull, eyelid, and anterior chamber anomalies, cleft lip and palate, umbilical anomalies, and growth and cognitive development.^{[2] [3]}

See also

• Malpuech facial clefting syndrome, another condition in the 3MC spectrum

Notes and References

1. Cunniff C, Jones KL . Craniosynostosis and lid anomalies: report of a girl with Michels syndrome . Am. J. Med. Genet. . 37 . 1 . 28–30 . September 1990 . 2240039 . 10.1002/ajmg.1320370108 .
2. Titomanlio L, Bennaceur S, Bremond-Gignac D, Baumann C, Dupuy O, Verloes A . Michels syndrome, Carnevale syndrome, OSA syndrome, and Malpuech syndrome: variable expression of a single disorder (3MC syndrome)? . Am. J. Med. Genet. A . 137A . 3 . 332–5 . September 2005 . 16096999 . 10.1002/ajmg.a.30878. 25690356 . free .
3. Al Kaissi A, Klaushofer K, Safi H, etal . Asymmetrical skull, ptosis, hypertelorism, high nasal bridge, clefting, umbilical anomalies, and skeletal anomalies in sibs: is Carnevale syndrome a separate entity? . Am. J. Med. Genet. A . 143 . 4 . 349–54 . February 2007 . 17236195 . 10.1002/ajmg.a.31610. 31561578 .