| Michele Somes Swanson | |
| Workplaces: | University of Michigan |
| Alma Mater: | Harvard University Yale University Columbia University |
| Thesis Title: | Analysis of SPT4, SPT5, and SPT6 interactions and effects on transcription in yeast |
| Thesis Url: | http://www.worldcat.org/oclc/26072086 |
| Thesis Year: | 1991 |
Michele S. Swanson is an American biologist who is a professor of microbiology at the University of Michigan. She has investigated the water-borne pathogen Legionella pneumophila. Swanson is interested in the metabolic cues that underpin the virulence of L. pneumophila and how it is transmitted to humans. She served as president of the American Society for Microbiology in 2018.
Swanson grew up in Michigan, one of six children in her family.[1] Her father was the first member of his family to attend university. Swanson spent her summer holidays playing sports at Michigan summer camps, where she played field hockey and softball. Swanson eventually earned her bachelor's degree at Yale University, where she worked as a counsellor for freshmen at Davenport College. Swanson was inspired by John Trinkaus to pursue a career in experimental biology. After graduating from Yale, Swanson joined Rockefeller University as a laboratory technician. She moved to Columbia University for her graduate studies, where she earned a master's degree in genetics under the supervision of Marian Carlson. Swanson joined the laboratory of Fred Winston at Harvard University where she completed her doctoral research on the interactions of various transcription factors with yeast.[2] She was a postdoctoral researcher at Tufts Medical Center, where she first became interested in Legionella pneumophila.
In 1996, Swanson joined the faculty at the University of Michigan. Swanson has studied how Legionella pneumophila remains virulent in different environments. She identified that the pathogen alternates between different cell types, one which is highly replicative and another which is highly transmissible that is primed to invade naïve hosts. After extended periods of starvation, L. pneumophila forms a highly infectious form. Swanson showed that L. pneumophila achieves these distinct cell types by coupling cellular differentiation to the metabolic state.
L. pneumophila can cause sporadic outbreaks of Legionnaires' disease. This was responsible for the Flint water crisis that started in 2014. Swanson has studied the mechanisms that permit L. pneumophila to persist in water, looking to create a microbiology based system to assess the safety of public water systems.[3]
Swanson serves as the director of postgraduate studies and President's Advisory Commission on Women's Issues at the University of Michigan. She was elected president of the American Society for Microbiology in 2018[4] and hosts the ASM podcast This Week in Microbiology.[5] She was elected Fellow of the American Association for the Advancement of Science in 2019.[6]