| Nationality: | Italian |
| Birth Place: | Crotone, Italy |
| Height: | 1.88m (06.17feet) |
| Weight: | 77kg (170lb) |
| Show-Medals: | yes |
Michele D'Oppido (born 10 February 1949) is a retired Italian swimmer. He competed at the 1968 Summer Olympics in the 100 m freestyle and 200 m and 400 m individual medley events, but failed to reach the finals. He finished fifth in the 200 m medley at the 1970 European Championships. His brother Antonio was also a competitive swimmer.