| Michael Otu | |
| Birth Date: | 25 October 1925 |
| Birth Place: | Adukrom, Ghana |
| Allegiance: |  Ghana |
| Branch: | Ghana Army |
| Serviceyears: | 1943 - 1971 |
| Rank: | Air Marshal |
| Commands: | Chief of Defence Staff Air Force Commander |
| Awards: | Order of the Star of Ghana |
| Relations: | Beatrice Agyepomaa Otu (wife) Abena, Emma, Kwame, Fiifi and Maama (children) |
Air Marshal Michael Akuoko Otu (25 October 1925 - 8 October 2006) was a senior commander in the Ghana Air Force who served as Chief of Air Staff and then Chief of Defence Staff of the Ghana Armed Forces.