| Nasir Muhammad Kalhoro | |
| Mian Nawab | |
| Reign: | 1657 – 1692 |
| Successor: | Deen Muhammad Kalhoro |
| Full Name: | Mian Nasir Muhammad Khan Kalhoro |
| House: | Kalhora dynasty |
| Religion: | Sunni Islam |
| Father: | Adam Shah Kalhoro |
| Birth Date: | 1627 |
| Death Date: | 1692 (aged 65) |
| Death Place: | Thatta, Thatta Subah, Mughal Empire |
Mian Nasir Muhammad Kalhoro (Urdu: {{nq|ميان نصير محمد کلہوڑو, Sindhi: ميان نصير محمد ڪلهوڙو) was a predecessor of the Kalhora dynasty. He was succeeded by his son Deen Muhammad. Nasir's tomb is sited in Dadu District, Khairpur Nathan Shah near the village of Garhi in Sindh, Pakistan.[1] [2]
Nasir Muhammad Kalhoro belonged to the Kalhora family whose first historical personality was Adam Shah Kalhoro whose shrine is at heart of the city Sukkur.[3] Nasir Muhammad succeeded legacy of forefathers and their Mianwal Movement which struggled against the Mughal Empire[4] He was a spiritual leader of the Mianwal Movement. During movement against Mughals, Nasir Muhammad Kalhoro was imprisoned by Mughals in Gwalior jail and was conditionally released from jail.