| Mezquital | |
| Settlement Type: | Municipality |
| Mapsize: | 300px |
| Pushpin Map: | Mexico |
| Pushpin Label Position: | above |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Durango |
| Subdivision Type2: | Municipal seat |
| Subdivision Name2: | San Francisco del Mezquital |
| Area Total Km2: | 7196.5 |
| Population As Of: | 2010 |
| Population Total: | 33,396 |
| Population Density Km2: | auto |
| Coordinates: | 23.4728°N -104.4111°W |
Mezquital is a municipality in the Mexican state of Durango. The municipal seat lies at San Francisco del Mezquital. The municipality covers an area of 7,196.5 km².
As of 2010, the municipality had a total population of 33,396,[1] up from 30,069 as of 2005.[2]
The municipality had 1,325 localities, the largest of which (with 2010 population in parentheses) was: San Francisco del Mezquital (1,742), classified as urban.[1]