The Mexican Road Race Championships are held annually by the Mexican Cycling Federation (es|Federación Mexicana de Ciclismo) to decide the Mexican cycling champions in the road race discipline, across various categories. The event was first held in 1998 and was won by Jesús Zárate.
| Mexican National Road Race Championships – Men's elite race | |
| Region: | Mexico |
| Discipline: | Road bicycle racing |
| Type: | One-day |
| First: | [1] |
| Firstwinner: | Jesús Zárate |
| Mostwins: | Luis Lemus (3 wins) |
| Mostrecent: | Efrén Santos |
| Year | Gold | Silver | Bronze | |
| 1998 | ||||
| 1999 | Omar Martínez | |||
| 2000 | José Luis Jiménez | |||
| 2001 | Andres Contreras | |||
| 2002 | Manuel Carbajal | |||
| 2003 | ||||
| 2004 | colspan=3 | |||
| 2005 | Ricardo Tapia | |||
| 2006 | Luis Fernando Macías | |||
| 2007 | Francisco Matamoros | |||
| 2008 | David Salomon | |||
| 2009 | Juan Pablo Magallanes | |||
| 2010 | Juan Manuel Sandoval | |||
| 2011 | Florencio Ramos | |||
| 2012 | Luis Pulido | |||
| 2013 | Luis Alvarez | |||
| 2014 | Francisco Matamoros | |||
| 2015 | Luis Alvarez | |||
| 2016 | Eder Frayre | |||
| 2017 | Uri Martins | |||
| 2018 | Ivan Carbajal | |||
| 2019 | Francisco Lara | |||
| 2020 | Emery Hernandez Vazquez | |||
| 2021 | Flavio de Luna | |||
| 2022 | Jorge Peyrot |
| Year | Gold | Silver | Bronze | |
| 2006 | Juan Enrique Diaz | |||
| 2007 | Omar Cervantes | |||
| 2008 | José Carlos Valdez | |||
| 2009 | Ivan Carbajal | |||
| 2010 | ||||
| 2011 | Ángel Portillo | |||
| 2012 | José Bravo |
| Mexican National Road Race Championships – Women's elite race | |
| Region: | Mexico |
| Discipline: | Road bicycle racing |
| Type: | One-day |
| First: | [2] |
| Firstwinner: | Giuseppina Grassi |
| Mostrecent: | Mariana Torres |
| Year | Gold | Silver | Bronze | |
| 1999 | Sonia López | |||
| 2000 | Claudia Verónica Leal Balderas | |||
| 2001 | Gabriella Gonzalez de Ferrat | |||
| 2002 | colspan=3 | |||
| 2003 | ||||
| 2004– 2005 | colspan=3 | |||
| 2006 | Maribel Díaz | |||
| 2007 | Giuseppina Grassi | |||
| 2008 | Laura Morfin | |||
| 2009 | Jessica Jurado | |||
| 2010 | Sofía Arreola | |||
| 2011 | Mayra Rocha | |||
| 2012 | Carolina Rodríguez | |||
| 2013 | Carolina Rodríguez | |||
| 2014 | Jenny Rios Piñal | |||
| 2015 | Marcela Prieto | |||
| 2016 | Sofía Arreola | |||
| 2017 | Marcela Prieto | |||
| 2018 | Cynthia Covarrubias | |||
| 2019 | Andrea Ramírez | |||
| 2020 | Brenda Santoyo | |||
| 2021 | Katia Martinez | |||
| 2022 | Anet Barrera |