| Country: | MEX |
| Type: | FH |
| Route: | 80 |
| Maint: | Secretariat of Communications and Transportation |
| Length Km: | 962.23 |
| Length Round: | 2 |
| Length Ref: | [1] [2] [3] |
| Direction A: | East |
| Terminus A: | in Tampico, Tamaulipas |
| Junction: | in Estación Manuel in González in Ciudad Mante in Antiguo Morelos in Tula Junction, San Luis Potosí in El Huizache in San Luis Potosí City in Ojuelos de Jalisco in Lagos de Moreno in Valle de Guadalupe near Tepatitlán in Zapotlanejo in Tlaquepaque in Guadalajara[4] in Acatlán de Juárez[5] near San Patricio |
| Direction B: | West |
| Previous Type: | FH |
| Previous Route: | 76 |
| Next Type: | FH |
| Next Route: | 81 |
Federal Highway 80 (Carretera Federal 80) connects Tampico, Tamaulipas, to San Patricio, Jalisco.[6] Federal Highway 80 connects the city of Guadalajara to the south coast in Jalisco. The highway runs through the towns of Acatlán de Juárez, Villa Corona, Cocula, Tecolotlán, Unión de Tula, Autlán, La Huerta, Casimiro Castillo, and San Patricio (Melaque).
Federal Highway 80 is interrupted in two different sections (as outlined by the SCT) of the otherwise contiguous route: Along Mexican Federal Highway 57 for 109.62 km from San Luis Potosí City to El Huizache in San Luis Potosí and along Mexican Federal Highway 85 for 31.1 km from Antiguo Morelos to Ciudad Mante in Tamaulipas.[7] [8]