| Country: | MEX |
| Type: | FH |
| Route: | 105 |
| Maint: | Secretariat of Communications and Transportation |
| Length Km: | 260.68 |
| Length Round: | 2 |
| Length Ref: | [1] |
| Direction A: | North |
| Terminus A: | in Tempoal de Sánchez[2] |
| Junction: | south of Huejutla de Reyes |
| Direction B: | South |
| Terminus B: | in Pachuca |
| Previous Type: | FH |
| Previous Route: | 103 |
| Next Type: | FH |
| Next Route: | 106 |
Federal Highway 105 (Carretera Federal 105) is a Federal Highway of Mexico.[3] The highway travels from Tempoal de Sánchez, Veracruz, in the north to Pachuca, Hidalgo, in the south.