Methylprednisolone aceponate explained

Methylprednisolone aceponate, or methylprednisolone acetate propionate, sold under the brand names Advantan and Avancort, is a glucocorticoid and a corticosteroid ester—specifically the C17α propionate and C21 acetate diester of methylprednisolone.[1] [2] [3]

In Russia and some other countries the drug is available in 4 dosage forms differing in consistency and water content: emulsion (or lotion), cream, ointment and fatty ointment.[4]

Synthesis

See also

Notes and References

  1. Book: J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 811–.
  2. Book: Index Nominum 2000: International Drug Directory. 2000. Taylor & Francis. 978-3-88763-075-1. 675–.
  3. Bieber T, Vick K, Fölster-Holst R, etal . Efficacy and safety of methylprednisolone aceponate ointment 0.1% compared to tacrolimus 0.03% in children and adolescents with an acute flare of severe atopic dermatitis . Allergy . 62 . 2 . 184–9 . February 2007 . 17298428 . 10.1111/j.1398-9995.2006.01269.x . 41761398 .
  4. Web site: Advantan (methylprednisolone aceponate) Full Prescribing Information Lists . State Register of Medicines . 31 March 2023 . Russian.