Methyldiazinol Explained

Methyldiazinol (also known as 3,3-azo-17α-methyl-5α-dihydrotestosterone, 3-azi-17α-methyl-DHT, or 3,3-azo-17α-methyl-5α-androstan-17β-ol) is a synthetic and orally active androgen/anabolic steroid (AAS) which was never marketed.^{[1] [2]} It is a 17α-methylated derivative of dihydrotestosterone (DHT); specifically, it is the C3 azi (i.e., 3,3-azo) analogue of mestanolone (17α-methyl-DHT). The drug has been found to possess a high ratio and dissociation of myotrophic to androgenic activity; relative to methyltestosterone, its ratio was 15 (3:0.2), among the highest observed.

See also

• List of androgens/anabolic steroids

Notes and References

1. Book: Kochakian CD . Anabolic-Androgenic Steroids. 6 December 2012. Springer Science & Business Media. 978-3-642-66353-6. 385. Methyldiazinol: 3-Azi-17-methyl-5α-androstan-17β-ol: The 3-azi derivative of methandrostanolone was noted by CHURCH et al. (1965) to have a wide myotrophic:androgenic dissociation (3: 0.2) 15 relative to methyltestosterone orally, among the highest noted..
2. Church RF, Kende AS, Weiss MJ . Diazirines. I. Some Observations on the Scope of the Ammonia-Hydroxylamine-O-sulfonic Acid Diaziridine Synthesis. The Preparation of Certain Steroid Diaziridines and Diazirines. Journal of the American Chemical Society. 87. 12. 1965. 2665–2671. 0002-7863. 10.1021/ja01090a025.