Methyl 2-fluoroacrylate explained

Methyl 2-fluoroacrylate (MFA) is a chemical compound classified as an acrylate ester. The molecular formula is C4H5FO2 and the molecular weight is 104.08. The systematic name of this chemical is methyl 2-fluoroprop-2-enoate. It is used in industrial chemistry to produce acrylate polymers with mechanical and optical properties,[1] and insect antifeedant 2-azabicyclo[2.1.1]hexane.[2]

Hazards

MFA is highly flammable and can be harmful if inhaled, in contact with skin, or if swallowed. It is irritating to eyes, respiratory system, and skin.[3]

Notes and References

  1. Fu . Boqiao . Cao . Zhen . Wu . Boying . Mao . Chongyang . Qin . Caiqin . Chen . Shigui . 2022-08-12 . Novel facile method for the synthesis of methyl 2-fluoro-3-hydroxypropanoate from Claisen salts and formaldehyde in water . Phosphorus, Sulfur, and Silicon and the Related Elements . 197 . 12 . 1277–1283 . 10.1080/10426507.2022.2097232 . 1042-6507.
  2. Wiesmann . U. N. . DiDonato . S. . Herschkowitz . N. N. . 1975-10-27 . Effect of chloroquine on cultured fibroblasts: release of lysosomal hydrolases and inhibition of their uptake . Biochemical and Biophysical Research Communications . 66 . 4 . 1338–1343 . 10.1016/0006-291x(75)90506-9 . 1090-2104 . 4.
  3. Material Safety Data Sheet. SynQuest Laboratories, Inc. Alachua, FL. Revised February, 2011

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