Methanosarcina-phenazine hydrogenase explained
| Methanosarcina-phenazine hydrogenase |
| Ec Number: | 1.12.98.3 |
| Cas Number: | 9027-05-8 |
| Go Code: | 0051911 |
In enzymology, a Methanosarcina-phenazine hydrogenase is an enzyme that catalyzes the chemical reaction
H2 + 2-(2,3-dihydropentaprenyloxy)phenazine
2-dihydropentaprenyloxyphenazine
Thus, the two substrates of this enzyme are H2 and 2-(2,3-dihydropentaprenyloxy)phenazine, whereas its product is 2-dihydropentaprenyloxyphenazine.
This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with other, known, acceptors. The systematic name of this enzyme class is hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase. Other names in common use include methanophenazine hydrogenase, and methylviologen-reducing hydrogenase.
References
- Abken HJ, Tietze M, Brodersen J, Baumer S, Beifuss U, Deppenmeier U . 1998 . Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Go1 . J. Bacteriol. . 180 . 2027 - 32 . 9555882 . 8 . 107126 .
- Deppenmeier U, Lienard T, Gottschalk G . 1999 . Novel reactions involved in energy conservation by methanogenic archaea . FEBS Lett. . 457 . 291 - 7 . 10471795 . 10.1016/S0014-5793(99)01026-1 . 3 . free .
- Beifuss U, Tietze M, Baumer S, Deppenmeier U . 2000 . Methanophenazine: Structure, Total Synthesis, and Function of a New Cofactor from Methanogenic Archaea This work was supported by the Deutsche Forschungsgemeinschaft (Sonderforschungsbereich 416; grants De 488/6-1 and De 488/4-2) and the Fonds der Chemischen Industrie We are grateful to Drs. J. Paust and H. Jaedicke (BASF AG, Ludwigshafen) and Dr. R. K. Muller (Hoffmann-La Roche Ltd., Basel) for generously providing chemicals . Angew. Chem. Int. Ed. Engl. . 39 . 2470 - 2472 . 10941105 . 14 . 10.1002/1521-3773(20000717)39:14<2470::AID-ANIE2470>3.0.CO;2-R .
