Methanophenazine Explained

Methanophenazine, a phenazine derivative, is a strongly hydrophobic redox-active cofactor with a role in electron transport in some methanogens.[1] This chromophore can be purified from membranes of methanogenic archaea such as Methanosarcina mazei. The enzyme methanosarcina-phenazine hydrogenase (EC 1.12.98.3) has the name methanophenazine hydrogenase as a synonym.

Notes and References

  1. Beifuss, Uwe . Tietze, Mario . Baumer, Sebastian . Deppenmeier, Uwe . Methanophenazine: structure, total synthesis, and function of a new cofactor from methanogenic Archaea . Angewandte Chemie International Edition . 2000 . 39 . 14 . 2470–2472 . 10.1002/1521-3773(20000717)39:14<2470::AID-ANIE2470>3.0.CO;2-R . 10941105.

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