Meteloidine Explained

Meteloidine is an alkaloid found in some Brugmansia and Datura species.[1] Its also found in Erythroxylum australe and is said to be cocaine-like alkaloid.[2]

Occurrence

The first report of the isolation from a natural source of meteloidine was in 1908 by Frank Lee Pyman and William Colebrook Reynolds[3] from the flowering plant Datura metel along Angelate ester and Datura meteloides (now reclassified as Datura innoxia).[4]

Meteloidine is primarily found in solanaceous plants, and in one species of genus Erythroxylum. It has been found in the leaves and flowers of Brugmansia candida,[5] and in the roots of Datura leichhardtii,[6] Brugmansia suaveolens,[7] Anthocercis littorea and Anthocercis viscosa[8] in minor quantities, and in Anthocercis genistoides as its principal alkaloid. Meteloidine has been identified in Erythroxylum australe, which is of chemotaxonomic interest as meteloidine has been found in a number of the Solanacae family, but in only one species in the family Erythroxylaceae.[9]

See also

Notes and References

  1. 6045963 . 1967 . Leete . E . Biosynthesis of the tiglic acid moiety of meteloidine in Datura meteloides . Tetrahedron Letters . 18 . 1727–30 . Murrill . J. B . 10.1016/s0040-4039(00)90710-x .
  2. Web site: Erowid Psychoactive Vaults : Australian Natural Highs FAQ.
  3. Pyman . Frank Lee . Meteloidine : A New Solanaceous Alkaloid . Journal of the Chemical Society . 1 January 1908 . 93 . 93 . 2077–2081 . 10.1039/CT9089302077 . 11 September 2021.
  4. Barclay . Arthur S . New Considerations in an Old Genus: Datura . Botanical Museum Leaflets, Harvard University . January 16, 1959 . 18 . 6 . 245–272 . 10.5962/p.168515 . 41762193 . 89207912 . free .
  5. Griffin . W J . Alkaloids in Datura, Section Brugmansia . Planta Medica . 1966 . 14 . 4 . 468–474 . 10.1055/s-0028-1100075 . 11 September 2021.
  6. Evans . W C . Studies on Datura Leichhardtii Muell. Ex Benth. . Journal of Pharmacy and Pharmacology . 1962 . 14 . 1 . 107T–110T . 10.1111/j.2042-7158.1962.tb10542.x . 85621808 .
  7. Evans . W C . Alkaloids of Datura suaveolens . Phytochemistry . November 1972 . 11 . 11 . 3293–3298 . 10.1016/s0031-9422(00)86392-x . 11 September 2021.
  8. El Imam . Y . Tropane Alkaloids of Species of Anthocercis, Cyphanthera and Crenidium . Planta Medica . 1984 . 50 . 1 . 86–87 . 10.1055/s-2007-969628 . 17340258 . 11 September 2021.
  9. Johns . S R . Meteloidine from Erythroxylum australe F. Muell . Australian Journal of Chemistry . 1967 . 20 . 6 . 1301–1302 . 10.1071/CH9671301 . free .

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