Mesoderm development LRP chaperone explained

Mesoderm development LRP chaperone, or MESD, is a protein that in humans is encoded by the MESD gene.^{[1] [2] [3]}

Further reading

• Nakajima D, Okazaki N, Yamakawa H, etal . Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. . DNA Res. . 9 . 3 . 99–106 . 2003 . 12168954 . 10.1093/dnares/9.3.99 . free .
• Scanlan MJ, Gordan JD, Williamson B, etal . Antigens recognized by autologous antibody in patients with renal-cell carcinoma. . Int. J. Cancer . 83 . 4 . 456–64 . 1999 . 10508479 . 10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5 . 21839750 .
• Dias Neto E, Correa RG, Verjovski-Almeida S, etal . Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. . Proc. Natl. Acad. Sci. U.S.A. . 97 . 7 . 3491–6 . 2000 . 10737800 . 10.1073/pnas.97.7.3491 . 16267 . 2000PNAS...97.3491D . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Hsieh JC, Lee L, Zhang L, etal . Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity. . Cell . 112 . 3 . 355–67 . 2003 . 12581525 . 10.1016/S0092-8674(03)00045-X . free .
• Clark HF, Gurney AL, Abaya E, etal . The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. . Genome Res. . 13 . 10 . 2265–70 . 2003 . 12975309 . 10.1101/gr.1293003 . 403697 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Veltman IM, Vreede LA, Cheng J, etal . Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25). . Hum. Mol. Genet. . 14 . 14 . 1955–63 . 2005 . 15917269 . 10.1093/hmg/ddi200 . free .
• Li Y, Lu W, He X, Bu G . Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd. . FEBS Lett. . 580 . 22 . 5423–8 . 2006 . 16989816 . 10.1016/j.febslet.2006.09.011 . 9683744 . free .

Notes and References

1. Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H . Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1 . DNA Res . 2 . 1 . 37–43 . Jul 1995 . 7788527 . 10.1093/dnares/2.1.37 . etal. free .
2. Wines ME, Lee L, Katari MS, Zhang L, DeRossi C, Shi Y, Perkins S, Feldman M, McCombie WR, Holdener BC . Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis . Genomics . 72 . 1 . 88–98 . Mar 2001 . 11247670 . 10.1006/geno.2000.6466 .
3. Web site: Entrez Gene: MESDC2 mesoderm development candidate 2.