| Merrill Creek | |
| Pushpin Map: | Canada Southern Ontario |
| Pushpin Map Caption: | Location of the mouth of Merrill Creek in southern Ontario |
| Subdivision Type1: | Country |
| Subdivision Name1: | Canada |
| Subdivision Type2: | Province |
| Subdivision Name2: | Ontario |
| Subdivision Type3: | Regions |
| Subdivision Type4: | Counties |
| Source1: | Unnamed lake |
| Source1 Location: | Addington Highlands, Lennox and Addington County |
| Source1 Coordinates: | 44.9489°N -77.3958°W |
| Source1 Elevation: | 368m (1,207feet) |
| Mouth: | Partridge Creek |
| Mouth Location: | Tweed, Hastings County |
| Mouth Coordinates: | 44.8892°N -77.4289°W |
| Mouth Elevation: | 331m (1,086feet) |
| River System: | Great Lakes Basin |
Merrill Creek is a creek in the Moira River and Lake Ontario drainage basins in Hastings and Lennox and Addington Counties, Ontario, Canada.
Merrill Creek begins at an unnamed lake in Addington Highlands, Lennox and Addington County at an elevation of 368m (1,207feet) and flows east and then south, through Todd Lakes, to reach Merrill Lake at an elevation of 338m (1,109feet). It heads south into Little Merrill Lake, then southwest to Whitefish Lake. Leaving the lake, the creek passes into the Cashel portion of Tudor and Cashel, Hastings County, then Tweed, Hastings County, and flows southwest to reach its mouth at Partridge Creek at an elevation of 331m (1,086feet). Partridge Creek flows via the Skootamatta River and Moira River to the Bay of Quinte on Lake Ontario at Belleville.