| Current: | 2024–25 Mercyhurst Lakers men's basketball team |
| Mercyhurst Lakers | |
| University: | Mercyhurst University |
| Conference: | Northeast Conference |
| Location: | Erie, Pennsylvania |
| Coach: | Gary Manchel |
| Tenure: | 22nd |
| Arena: | Mercyhurst Athletic Center |
| Capacity: | 1,100 |
| Nickname: | Lakers |
| Ncaaeliteeight: | Division II: 2019 |
| Ncaasweetsixteen: | Division II: 2019 |
| Ncaaroundof32: | Division II: 2016, 2019, 2021, 2022, 2023 |
| Ncaatourneys: | Division II: 2015, 2016, 2019, 2020, 2021, 2022, 2023 |
| Conference Tournament: | PSAC 2016 |
The Mercyhurst Lakers men's basketball team represents Mercyhurst University in Erie, Pennsylvania. Beginning on July 1, 2024, the Lakers will compete in the Division I Northeast Conference. Due to the NCAA's policy on reclassifying programs, the Lakers will not be eligible to compete in the NCAA tournament or the NIT until the 2028–29 season.
The Lakers appeared in the NCAA Division II tournament seven times. Their combined record was 7–6.
| 2015 | Regional first round | Fairmont State | L 63–68 | |
| 2016 | Regional first round Regional semifinals | Wheeling Jesuit Kutztown | W 66–65 L 73–79 | |
| 2019 | Regional first round Regional semifinals Regional finals Elite Eight | Fairmont State IUP West Liberty Northwest Missouri State | W 63–60 OT W 75–65 W 82–70 L 51–55 | |
| 2020 | Regional first round | University of Charleston | COVID-19 | |
| 2021 | Regional first round Regional semifinals | Fairmont State Hillsdale | W 62–58 L 48–67 | |
| 2022 | Regional first round Regional semifinals | Millersville IUP | W 71–65 L 55–58 | |
| 2023 | Regional first round Regional semifinals | East Stroudsburg West Liberty | W 72–66 L 72–86 |