| Mercer Area Middle-High School | |
| Streetaddress: | 545 W. Butler Street |
| City: | Mercer |
| State: | Pennsylvania |
| Zipcode: | 16137 |
| Country: | United States |
| District: | Mercer Area School District |
| Principal: | Eric Mausser |
| Type: | Public, Middle, Secondary |
| Grades: | 7–12 |
| Campus: | Rural |
| Conference: | District 10 Region 1 Conference |
| Nickname: | Mustangs |
Mercer Area High School is a high school located in Mercer, Pennsylvania, United States. The school's colors are navy blue and white. The school mascot is the Mercer Mustang.