Meningioangiomatosis Explained

Specialty:	neurology

Meningioangiomatosis is a rare disease and tauopathy of the brain. It is characterized by a benign lesion of the leptomeninges usually involving the cerebral cortex, and by leptomeningeal and meningovascular proliferation.^[1] Often the patient will present with seizures. The disease may be either sporadic or associated with neurofibromatosis type 2. The lesion is usually focused in one place, though extremely rare multifocal cases have been reported in both adults and children.^[2] Biopsy is usually necessary for diagnosis. Treatment conventionally involves surgical removal of the lesion.

Further reading

• Feng R, Hu J, Che X, Pan L, Wang Z, Zhang M, Huang F, Xu B, Mao R, Sun A, Bao W, Zhong P, Wang Y . Diagnosis and surgical treatment of sporadic meningioangiomatosis . Clinical Neurology and Neurosurgery . 115 . 8 . 2013 . 1407–14 . 23485253 . 10.1016/j.clineuro.2013.01.021. 26535825 .
• Barbosa-Silva E, Dellaretti M, de Carvalho GT, Pereira JL, ((Botrel L Jr)), Pittella JE, de Sousa AA . Meningioangiomatosis without neurofibromatosis simulating encephalitis in neuroimaging . Surgical Neurology International . 3 . 2012 . 34 . 22530169 . 3326948 . 10.4103/2152-7806.94035 . free .
• Rev Neurol (Paris) . Dec 2011 . 167 . 12 . 886–96 . Seizures in neurofibromatosis. What is the risk? . Neurofibromatoses : quel risque épileptique ? . French . Drouet A . 22041820 . 10.1016/j.neurol.2011.04.009 .

Notes and References

1. Wiebe. S.. Meningioangiomatosis: A comprehensive analysis of clinical and laboratory features. Brain. 1 April 1999. 122. 4. 709–726. 10.1093/brain/122.4.709. 10219783 . free.
2. Jamil O, Ramkissoon S, Folkerth R, Smith E . Multifocal meningioangiomatosis in a 3-year-old patient . Case report . Journal of Neurosurgery: Pediatrics . 10 . 6 . 2012 . 486–9 . 23020197 . 3762590 . 10.3171/2012.9.PEDS1224.