Melothria pringlei is a species of flowering plant in the cucurbit family, with a native range spanning Mexico to Honduras. It was first described by Sereno Watson in 1890 and placed in the genus Apodanthera,[1] but was reclassified as belonging to the genus Melothria in 1954 by Raul Martinez Crovetto.[2] Melothria pringlei has a prostrate habit, with scabrous stems that root where they touch the ground. Its leaves are scabrous and lobed, and grow NaN1NaN1 in length, with a slightly smaller width.[3] It is a monoecious species,[4] with each plant producing both male (staminate) and female (pistillate) flowers, which are small.