| Melissa | |
| Official Name: | Comune di Melissa |
| Coordinates: | 39.3083°N 17.0278°W |
| Region: | Calabria |
| Province: | Crotone (KR) |
| Frazioni: | Torre Melissa |
| Mayor: | Raffaele Falbo |
| Area Total Km2: | 51 |
| Population Footnotes: | [1] |
| Population Total: | 3624 |
| Population As Of: | 2011 |
| Population Demonym: | Melissesi |
| Elevation M: | 256 |
| Saint: | Saint Nicholas |
| Postal Code: | 88817 (88814 Torre Melissa) |
| Area Code: | 0962 |
Melissa (Calabrian: Neapolitan: Mèlissë) is a comune in the province of Crotone, in Calabria. The village Melissa is situated in the mountainous inland, while the frazione of Torre Melissa is on the Ionian Sea coast. The Melissa DOC is a Calabrian wine region.
Melissa is mentioned for the first time in 13th century documents. It was a fief of the de Micheli family (1463 - 66), Venetian nobles based in Calabria, of the Campitelli family (1485 - 1688) and, later, to the Pignatelli (1688 - 1806).
In 1949 it was the location of a massacre, when the police shot against the population, killing three people.
Melissa is twinned with:
Gattatico, Italy Sant'Ilario d'Enza, Italy