| Melanthio | |
| Type: | community |
| Coordinates: | 40.3958°N 21.1292°W |
| Periph: | Western Macedonia |
| Periphunit: | Kastoria |
| Municipality: | Argos Orestiko |
| Municunit: | Argos Orestiko |
| Population As Of: | 2021 |
| Population: | 104 |
| Georegion: | Macedonia |
Melanthio (Greek, Modern (1453-);: Μελάνθιο, before 1927: Ζαμπύρδενη – Zampyrdeni[1]) is a village and a community in Kastoria Regional Unit, Macedonia, Greece. The community consists of the villages Melanthio, Niki and Petropoulaki.
The Greek census (1920) recorded 592 people in the village and in 1923 there were 600 inhabitants (or 70 families) who were Muslim. Following the Greek–Turkish population exchange, in Zampyrdeni there were 69 refugee families from Pontus in 1926. The Greek census (1928) recorded 320 village inhabitants. In 1928 there were 72 refugee families (309 people).[2]