| Mel Semenko | |
| Birth Date: | 26 November 1937 |
| Birth Place: | Baton Rouge, Louisiana, U.S. |
| Death Place: | Wexford, Pennsylvania, U.S. |
| Status: | Retired |
| Import: | yes |
| Position1: | Defensive end |
| Height Ft: | 6 |
| Height In: | 2 |
| Weight Lb: | 235 |
| College: | Colorado |
| Nfldraftedyear: | 1959 |
| Nfldraftedround: | 27 |
| Nfldraftedpick: | 318 |
| Nfldraftedteam: | San Francisco 49ers |
| Afldraftedyear: | 1960 |
| Afldraftedround: | 2 |
| Afldraftedpick: | First Selections |
| Afldraftedteam: | Denver Broncos |
| Playing Team1: | BC Lions |
| Playing Years2: | - |
| Playing Team2: | Ottawa Rough Riders |
| Playing Years3: | 1963 |
| Playing Team3: | Montreal Alouettes |
| Career Highlights: | |
Melvin Roy Semenko (December 12, 1937 – March 24, 2023) was a Canadian football player who played for the BC Lions, Ottawa Rough Riders and Montreal Alouettes. He played college football at the University of Colorado.[1]
Semenko died in Wexford, Pennsylvania on March 24, 2023, at the age of 85.[2]