| Official Name: | Mekoni |
| Native Name: | መኾኒ |
| Settlement Type: | Town |
| Pushpin Map: | Ethiopia |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location within Ethiopia |
| Coordinates: | 12.8028°N 77.754°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Ethiopia |
| Subdivision Type1: | Region |
| Subdivision Type2: | Zone |
| Subdivision Name2: | Dubawi (Southern) |
| Subdivision Type3: | Woreda |
| Subdivision Name3: | Raya Azebo |
| Elevation M: | 2479 |
| Population Total: | 9,419 |
| Population As Of: | 2007 |
| Timezone: | EAT |
| Utc Offset: | +3 |
Mekoni, also Mehoni (Ge'ez: መኾኒ or መሆኒ), is a town in the Tigray Region of Ethiopia. "Mekoni" (pronounced as 'Me-koni') is located at 657 km north of Addis Ababa along Ethiopian Highway 2 which runs to Mekelle (the capital city of Tigray region), Adigrat, Aksum, Shire and Humera with an altitude of 2479 m.
The town's economy is agriculturally focused. In recent years, there have been construction of irrigated and terraced farming in order to fight desertification.[1]