Iotroxic acid explained

Iotroxic acid (trade name Biliscopin), used in the form of meglumine iotroxate, is a molecule used as a contrast medium during X-rays.[1] It is specifically used during tests looking at the gallbladder and biliary tract. It is given by slow injection into a vein.

Side effects are uncommon.[2] They include vomiting, skin flushing, headache, itchiness, and low blood pressure. Rare side effects include seizures and allergic reactions. It should not be used by those who have an iodine allergy.[3] Iotroxic acid is an iodine containing contrast media of the diionic dimer type.[4]

Iotroxic acid was first made in 1976.[5] It is on the World Health Organization's List of Essential Medicines.[6] It is rarely used in the developed world due to the availability of magnetic resonance cholangiopancreatography (MRCP).[7]

Notes and References

  1. Web site: Iotroxic Acid . Drugs.com. 31 December 2016. live. https://web.archive.org/web/20161231170334/https://www.drugs.com/international/iotroxic-acid.html. 31 December 2016.
  2. Book: Neugebauer E, Sauerland S . Diagnosis and treatment of common bile duct stones . Recommendations for evidence-based endoscopic surgery: The updated EAES consensus development conferences. 2014. Springer Science & Business Media. 9782817808499. 67. https://books.google.com/books?id=seILBwAAQBAJ&pg=PA67. live. https://web.archive.org/web/20170101000948/https://books.google.ca/books?id=seILBwAAQBAJ&pg=PA67. 2017-01-01.
  3. Book: WHO Model Formulary 2008 . 2009 . 9789241547659 . ((World Health Organization)) . Stuart MC, Kouimtzi M, Hill SR . 10665/44053 . World Health Organization . World Health Organization . free . 315, 318 .
  4. Book: Schaefer C, Peters PW, Miller RK . Iodine containing contrast media . Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment. 2014. Academic Press. 9780124079014. 532. https://books.google.com/books?id=L2NzAwAAQBAJ&pg=PA532 . live. https://web.archive.org/web/20170101001148/https://books.google.ca/books?id=L2NzAwAAQBAJ&pg=PA532. 2017-01-01.
  5. Book: Korolkovas A . Essentials of Medicinal Chemistry. 1988. Wiley. 9780471883562. 1063. live. https://web.archive.org/web/20170101001146/https://books.google.ca/books?id=6hxtAAAAMAAJ. 2017-01-01.
  6. Book: ((World Health Organization)) . World Health Organization model list of essential medicines: 21st list 2019 . 2019 . 10665/325771 . World Health Organization . World Health Organization . Geneva . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO . free .
  7. Book: Sherlock S, Dooley J . Imaging of the Biliary Tract: Interventional Radiology and Endoscopy . Diseases of the Liver and Biliary System. 2008. John Wiley & Sons. 9780470986813. 568. https://books.google.com/books?id=-TD1_-SiqvcC&pg=PA568. live. https://web.archive.org/web/20170101001040/https://books.google.ca/books?id=-TD1_-SiqvcC&lpg=PA568. 2017-01-01.

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